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A highly selective inhibitor of Wnt pathway, as a potential topical treatment for cancer

Wnt inhibitors

Pim Kinase / April 6, 2026

The ratio of live to useless cells was calculated using the ImageJ 1

The ratio of live to useless cells was calculated using the ImageJ 1.43e software program (Wayne Rasband, NIH, USA). TherosRmutants are even more…

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Growth Factor Receptors / April 5, 2026

The 19q12 amplicon can therefore be mapped to a region spanning 34

The 19q12 amplicon can therefore be mapped to a region spanning 34.435.4 of chromosome 19 and involving 5 annotated genes, each of which…

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Other Peptide Receptors / April 3, 2026

The clamp base in NAD+-reliant DNA ligases, alternatively, is formed by a couple of four helix-hairpin-helix (HhH) motifs, that are from the N-terminal from the NTBDviaa structural zinc-binding domain50,56

The clamp base in NAD+-reliant DNA ligases, alternatively, is formed by a couple of four helix-hairpin-helix (HhH) motifs, that are from the N-terminal…

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Carbonic acid anhydrate / April 2, 2026

A mild maculopapular rash developed in three volunteers (two vaccinees and one placebo)

A mild maculopapular rash developed in three volunteers (two vaccinees and one placebo). 10% of the rDEN430-4995 vaccinees. None of the rDEN430-4995 vaccinees…

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CysLT1 Receptors / April 1, 2026

The degradation of SPARC by proteases has been shown as a valid mechanism for the liberation of biologically active peptides from the parent sequence (for review, see Ref

The degradation of SPARC by proteases has been shown as a valid mechanism for the liberation of biologically active peptides from the parent…

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Miscellaneous GABA / March 31, 2026

Most get away mutants cluster in the membrane-distal site, coincident using the antigenic sites in H3 (Fig

Most get away mutants cluster in the membrane-distal site, coincident using the antigenic sites in H3 (Fig.4a and b). elongation of receptor-binding sites…

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Sodium/Calcium Exchanger / March 30, 2026

The presence of HCV RNA in the anti-HCV-positive samples was assessed by reverse transcription-polymerase chain reaction (RT-PCR)

The presence of HCV RNA in the anti-HCV-positive samples was assessed by reverse transcription-polymerase chain reaction (RT-PCR). health problem worldwide, with ever-increasing interest…

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Sigma-Related / March 29, 2026

This HR varied as time passes and was significant for the first two years rather than significant after two years

This HR varied as time passes and was significant for the first two years rather than significant after two years. == Summary ==…

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Nitric Oxide Precursors / March 28, 2026

Because the sequence of MqsR is not similar to that of some other known toxin, its molecular function is unknown

Because the sequence of MqsR is not similar to that of some other known toxin, its molecular function is unknown. Deletion ofmqsA(ygiT/b3021), the…

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Glutamate (EAAT) Transporters / March 14, 2026

The last mentioned steps derive from the observed ability from the plasma cell-associated factor XBP-1s to transactivate the critical viral promoters involved with driving expression from the EBV and KSHV lytic switch genes[8],[9],[10],[11],[12]

The last mentioned steps derive from the observed ability from the plasma cell-associated factor XBP-1s to transactivate the critical viral promoters involved with…

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